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You should not use nitroglycerin if you are allergic to it, or if:

  • you are using medicine to treat pulmonary arterial hypertension (PAH), such as riociguat (Adempas), sildenafil (Revatio), or tadalafil (Adcirca).

Do not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking nitroglycerin. Using erectile dysfunction medicine with nitroglycerin can cause a sudden and serious decrease in blood pressure.

You should not use nitroglycerin if you have:

  • severe anemia (low red blood cells);
  • a head injury, brain tumor, or other condition that causes increased pressure inside the skull; or
  • symptoms of circulation problems or shock (pale skin, cold sweat, fast or irregular heartbeats, sudden weakness or feeling like you might pass out).

To make sure nitroglycerin is safe for you, tell your doctor if you have:

  • congestive heart failure;
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  • a history of heart attack, stroke, or head injury;
  • low blood pressure;
  • glaucoma;
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  • It is not known whether nitroglycerin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
  • It is not known whether nitroglycerin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

You should not use Nitrostat if you are also using medicine to treat pulmonary arterial hypertension (PAH).
Do not take erectile dysfunction medicine (Viagra, Cialis, Levitra and others) while you are taking nitroglycerin, or you could have a sudden and serious decrease in blood pressure.
Seek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating, general ill feeling).

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